Behavioral Neurobiology of Psychedelic Drugs

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Beschreibung

This volume brings together the latest basic and clinical research examining the effects and underlying mechanisms of psychedelic drugs. Examples of drugs within this group include LSD, psilocybin, and mescaline. Despite their structural differences, these compounds produce remarkably similar experiences in humans and share a common mechanism of action. Commonalities among the substances in this family are addressed both at the clinical and phenomenological level and at the basic neurobiological mechanism level. To the extent possible, contributions relate the clinical and preclinical findings to one another across species. The volume addresses both the risks associated with the use of these drugs and the potential medical benefits that might be associated with these and related compounds.

Zusammenfassung

The volume brings together clinical and preclinical research literatures

A balanced view of the potential risks and benefits of these compounds is presented

The focus is on rigorous scientific findings in a field that has been fraught with speculative reports

Inhaltsverzeichnis

Preface.- Chemistry and structure-activity relationships of psychedelics.- Hallucinogens and serotonin 5-HT2A receptor-mediated signaling pathways.- Effects of hallucinogens on neuronal activity.- Interactions of Hallucinogens with the Glutamatergic System: Permissive Network Effects Mediated Through Cortical Layer V Pyramidal Neurons.- The effects of hallucinogens on gene expression.- Effect of Hallucinogens on Unconditioned Behavior.- Hallucinogens in Drug Discrimination.- Phenomenology, structure and dynamic of psychedelic states.- Serotonergic hallucinogen-induced visual perceptual alterations.- New world tryptamine hallucinogens and the neuroscience of ayahuasca.- Experimental psychosis research and schizophrenia - similarities and dissimilarities in psychopathology.- A review of Hallucinogen Persisting Perception Disorder (HPPD) and an exploratory study of subjects claiming symptoms of HPPD.- Therapeutic applications of classic hallucinogens.- Classic Hallucinogens and Mystical Experiences: Phenomenology and Neural Correlates.

Details

Erscheinungsjahr:	2019
Fachbereich:	Therapie
Genre:	Medizin
Rubrik:	Wissenschaften
Medium:	Taschenbuch
Reihe:	Current Topics in Behavioral Neurosciences
Inhalt:	x 430 S. 38 s/w Illustr. 158 farbige Illustr. 430 p. 196 illus. 158 illus. in color.
ISBN-13:	9783662585634
ISBN-10:	3662585634
Sprache:	Englisch
Ausstattung / Beilage:	Paperback
Einband:	Kartoniert / Broschiert
Redaktion:	Halberstadt, Adam L. Nichols, David E. Vollenweider, Franz X.
Herausgeber:	Adam L Halberstadt/Franz X Vollenweider/David E Nichols
Auflage:	Softcover reprint of the original 1st ed. 2018
Hersteller:	Springer-Verlag GmbH Springer Berlin Heidelberg Current Topics in Behavioral Neurosciences
Maße:	235 x 155 x 24 mm
Von/Mit:	Adam L. Halberstadt (u. a.)
Erscheinungsdatum:	19.01.2019
Gewicht:	0,668 kg