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Cover: 9781137543325 | Biology, Computing, and the History of Molecular Sequencing | Buch
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Biology, Computing, and the History of Molecular Sequencing
From Proteins to Dna, 1945-2000
Taschenbuch von M. García-Sancho
Sprache: Englisch

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Beschreibung
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Über den Autor
Miguel Garcia-Sancho obtained his Ph.D. at Imperial College London, UK, and has worked at the University of Manchester and Spanish National Research Council (CSIC). He is currently a Chancellor's Fellow at the Department of Science, Technology and Innovation Studies of the University of Edinburgh. His interests lay in the history and social studies of twentieth century biomedicine, as well as science communication and free-lance scientific journalism.
Zusammenfassung
The first academic history of sequencing, a practice which emerged in 1940s protein chemistry and by the end of the 20th century transformed biology with the Human Genome Project
Inhaltsverzeichnis
Introduction: An Historical Approach to Sequencing PART I: EMERGENCE: FREDERICK SANGER'S PIONEERING TECHNIQUES (1943-1977) The Sequence of Insulin and the Configuration of a New Biochemical Form of Work (1943-1962) From Chemical Degradation to Biological Replication (1962-1977) PART II: MECHANISATION - 1: COMPUTING AND THE AUTOMATION OF SEQUENCE RECONSTRUCTION (1962-1987) Sequencing Software and the Shift in the Practice of Computation Sequence Databases and the Emergence of 'Information Engineers' PART III: MECHANISATION - 2: THE SEQUENCER AND THE AUTOMATION OF SEQUENCE CONSTRUCTION (1980-2000) A New Approach to Sequencing at Caltech The Commercialisation of the DNA Sequencer Conclusions: A Long History of Practices Appendix 1: Oral Histories Appendix 2: Archival Sources Notes Bibliography
Details
Erscheinungsjahr: 2012
Fachbereich: Biophysik
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Inhalt: xiii
242 S.
ISBN-13: 9781137543325
ISBN-10: 1137543329
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: García-Sancho, M.
Auflage: 2012 edition
Hersteller: Palgrave Macmillan
Palgrave MacMillan UK
Maße: 216 x 139 x 20 mm
Von/Mit: M. García-Sancho
Erscheinungsdatum: 11.05.2012
Gewicht: 0,317 kg
Artikel-ID: 104809637
Über den Autor
Miguel Garcia-Sancho obtained his Ph.D. at Imperial College London, UK, and has worked at the University of Manchester and Spanish National Research Council (CSIC). He is currently a Chancellor's Fellow at the Department of Science, Technology and Innovation Studies of the University of Edinburgh. His interests lay in the history and social studies of twentieth century biomedicine, as well as science communication and free-lance scientific journalism.
Zusammenfassung
The first academic history of sequencing, a practice which emerged in 1940s protein chemistry and by the end of the 20th century transformed biology with the Human Genome Project
Inhaltsverzeichnis
Introduction: An Historical Approach to Sequencing PART I: EMERGENCE: FREDERICK SANGER'S PIONEERING TECHNIQUES (1943-1977) The Sequence of Insulin and the Configuration of a New Biochemical Form of Work (1943-1962) From Chemical Degradation to Biological Replication (1962-1977) PART II: MECHANISATION - 1: COMPUTING AND THE AUTOMATION OF SEQUENCE RECONSTRUCTION (1962-1987) Sequencing Software and the Shift in the Practice of Computation Sequence Databases and the Emergence of 'Information Engineers' PART III: MECHANISATION - 2: THE SEQUENCER AND THE AUTOMATION OF SEQUENCE CONSTRUCTION (1980-2000) A New Approach to Sequencing at Caltech The Commercialisation of the DNA Sequencer Conclusions: A Long History of Practices Appendix 1: Oral Histories Appendix 2: Archival Sources Notes Bibliography
Details
Erscheinungsjahr: 2012
Fachbereich: Biophysik
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Inhalt: xiii
242 S.
ISBN-13: 9781137543325
ISBN-10: 1137543329
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: García-Sancho, M.
Auflage: 2012 edition
Hersteller: Palgrave Macmillan
Palgrave MacMillan UK
Maße: 216 x 139 x 20 mm
Von/Mit: M. García-Sancho
Erscheinungsdatum: 11.05.2012
Gewicht: 0,317 kg
Artikel-ID: 104809637
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