Peter Hindmarsh is a Professor of Pediatric Endocrinology in London, United Kingdom. He has published extensively on cortisol physiology and pharmacology and how these impact on replacement therapies for adrenal insufficiency. He is interested in better delivery of treatment in a more physiological manner as exemplified by the delivery of hydrocortisone using pump therapy to mimic the circadian rhythm.

Section One: Congenital adrenal hyperplasia-introduction1. Physiology of the Adrenal Glands: How Does It Work?2. How Males and Females Develop3. Genetics of Congenital Adrenal Hyperplasia4. Common Forms of Congenital Adrenal Hyperplasia5. Other Blocks in the Pathway Causing Congenital Adrenal Hyperplasia6. Growth7. Puberty8. Biochemical Tests Used for Diagnosis

Section Two: When things go wrong in congenital adrenal hyperplasia9. Monitoring Long Term Outcomes10. Growth11. When Things Go Wrong With Puberty12. When Things Go Wrong-Weight, Diabetes and Hypertension13. When Things Go Wrong-Bone Density and Osteoporosis14. Fertility15. Sleep and Mood Alterations16. Abdominal, Skin and Other Problems

Section Three: Treatment for congenital adrenal hyperplasia17. History of Steroid Development18. Glucocorticoid Treatment19. Glucose and Cortisol20. Hydrocortisone21. Dosing and the Circadian Rhythm22. Cortisol and 17-Hydroxyprogesterone23. Using Profiles to Assess Cortisol Replacement24. Monitoring Hydrocortisone Therapy25. Other Hormones and Their Roles26. Missing a Dose of Hydrocortisone27. Intravenous, Intramuscular and Other Forms of Hydrocortisone28. The Pump Method for Achieving a Normal Circadian Cortisol Replacement29. Stress Dosing for Sick Days, Surgery, Exams and Exercise30. Practical Information Emergency Kit and School Information31. Other Treatments for Congenital Adrenal Hyperplasia-Prednisolone, Dexamethasone and Adrenalectomy32. Fludrocortisone 9 Alpha-Fludrocortisone33. Travel and Time Zones34. Thinking Through Blood Results-A Quiz35. Discussing the Emotional Aspects of Living With Congenital Adrenal HyperplasiaAppendix 1. Converting System International (SI) Blood Measures Into North American Values or Conventional UnitsAppendix 2. List of Abbreviations