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Includes cutting-edge, fully updated techniques
Provides step-by-step detail essential for reproducible results
Contains key implementation advice from the experts
In Vitro Models in Developmental Toxicology.- Use of Primary Mouse Embryonic Fibroblasts in Developmental Toxicity Assessments.- Induced Pluripotent Stem Cells (iPSCs) in Developmental Toxicology.- Neural Crest Cell Models of Development and Toxicity: Cytotoxicity Assay Using Human Pluripotent Stem Cell-Derived Cranial Neural Crest Cell Model.- Micromass Methods for the Evaluation of Developmental Toxicants.- The Murine Limb Bud in Culture as an In Vitro Teratogenicity Test System.- Embryonic Mid-Facial Palatal Organ Culture Methods in Developmental Toxicology.- Ex Vivo Fetal Whole Ovarian Culture Model: An Essential Tool for Studies in Reproductive Toxicology and Pharmacology.- Hepatotoxicity in Zebrafish Larvae.- Drosophila as a Model for Developmental Toxicology: Using and Extending the DrosophotoxicologyModel.- The Chicken Embryo as a Model in Developmental Toxicology.- The Xenopus tropicalis Model for Studies of Developmental and Reproductive Toxicity.- Mouse Whole Embryo Culture.- Rat Whole Embryo Culture.- Rabbit Whole Embryo Culture.- Genome Editing in Zebrafish Using CRISPR-Cas9: Applications for Developmental Toxicology.- Identifying Toxicant-Interacting Genes Using Forward-Genetic Screening in Zebrafish.- Assessment of Histiotrophic Nutrition Using Fluorescent Probes.- Examining Gene Expression Patterns through Whole Mount In Situ Hybridization.- Confocal Laser Scanning Microscopy of Morphology and Apoptosis in Organogenesis-Stage Mouse Embryos.- Measurement of the Oxidative DNA Lesion 8-Oxoguanine (8-oxoG) by ELISA or by High-Performance Liquid Chromatography (HPLC) with Electrochemical Detection.- Quantifying Activity for Repair of the DNA Lesion 8-Oxoguanine by Oxoguanine Glycosylase 1 (OGG1) in Mouse Adult and Fetal Brain Nuclear Extracts Using Biotin-Labeled DNA.- Western Analysis of Breast Cancer 1 Protein (BRCA1).- Regulation and Control of AP-1 Binding Activity in Embryotoxicity.- Characterization of Epigenetic Histone Activation/Repression Marks in Sequences of Genes by Chromatin Immunoprecipitation-Quantitative Polymerase Chain Reaction (ChIP-qPCR).- The Application of High-Resolution Ultrasound for Assessment of Cardiac Structure and Function Associated with Developmental Toxicity.- Assessment of Gross Fetal Malformations: The Modernized Wilson Technique and Skeletal Staining.
Erscheinungsjahr: | 2019 |
---|---|
Fachbereich: | Toxikologie |
Genre: | Medizin |
Rubrik: | Wissenschaften |
Medium: | Buch |
Reihe: | Methods in Molecular Biology |
Inhalt: |
xi
436 S. 51 s/w Illustr. 104 farbige Illustr. 436 p. 155 illus. 104 illus. in color. |
ISBN-13: | 9781493991815 |
ISBN-10: | 1493991817 |
Sprache: | Englisch |
Herstellernummer: | 978-1-4939-9181-5 |
Ausstattung / Beilage: | HC runder Rücken kaschiert |
Einband: | Gebunden |
Redaktion: |
Winn, Louise M.
Hansen, Jason M. |
Herausgeber: | Jason M Hansen/Louise M Winn |
Auflage: | 2nd ed. 2019 |
Hersteller: |
Springer US
Springer New York Methods in Molecular Biology |
Maße: | 260 x 183 x 30 mm |
Von/Mit: | Louise M. Winn (u. a.) |
Erscheinungsdatum: | 09.05.2019 |
Gewicht: | 1,034 kg |
Includes cutting-edge, fully updated techniques
Provides step-by-step detail essential for reproducible results
Contains key implementation advice from the experts
In Vitro Models in Developmental Toxicology.- Use of Primary Mouse Embryonic Fibroblasts in Developmental Toxicity Assessments.- Induced Pluripotent Stem Cells (iPSCs) in Developmental Toxicology.- Neural Crest Cell Models of Development and Toxicity: Cytotoxicity Assay Using Human Pluripotent Stem Cell-Derived Cranial Neural Crest Cell Model.- Micromass Methods for the Evaluation of Developmental Toxicants.- The Murine Limb Bud in Culture as an In Vitro Teratogenicity Test System.- Embryonic Mid-Facial Palatal Organ Culture Methods in Developmental Toxicology.- Ex Vivo Fetal Whole Ovarian Culture Model: An Essential Tool for Studies in Reproductive Toxicology and Pharmacology.- Hepatotoxicity in Zebrafish Larvae.- Drosophila as a Model for Developmental Toxicology: Using and Extending the DrosophotoxicologyModel.- The Chicken Embryo as a Model in Developmental Toxicology.- The Xenopus tropicalis Model for Studies of Developmental and Reproductive Toxicity.- Mouse Whole Embryo Culture.- Rat Whole Embryo Culture.- Rabbit Whole Embryo Culture.- Genome Editing in Zebrafish Using CRISPR-Cas9: Applications for Developmental Toxicology.- Identifying Toxicant-Interacting Genes Using Forward-Genetic Screening in Zebrafish.- Assessment of Histiotrophic Nutrition Using Fluorescent Probes.- Examining Gene Expression Patterns through Whole Mount In Situ Hybridization.- Confocal Laser Scanning Microscopy of Morphology and Apoptosis in Organogenesis-Stage Mouse Embryos.- Measurement of the Oxidative DNA Lesion 8-Oxoguanine (8-oxoG) by ELISA or by High-Performance Liquid Chromatography (HPLC) with Electrochemical Detection.- Quantifying Activity for Repair of the DNA Lesion 8-Oxoguanine by Oxoguanine Glycosylase 1 (OGG1) in Mouse Adult and Fetal Brain Nuclear Extracts Using Biotin-Labeled DNA.- Western Analysis of Breast Cancer 1 Protein (BRCA1).- Regulation and Control of AP-1 Binding Activity in Embryotoxicity.- Characterization of Epigenetic Histone Activation/Repression Marks in Sequences of Genes by Chromatin Immunoprecipitation-Quantitative Polymerase Chain Reaction (ChIP-qPCR).- The Application of High-Resolution Ultrasound for Assessment of Cardiac Structure and Function Associated with Developmental Toxicity.- Assessment of Gross Fetal Malformations: The Modernized Wilson Technique and Skeletal Staining.
Erscheinungsjahr: | 2019 |
---|---|
Fachbereich: | Toxikologie |
Genre: | Medizin |
Rubrik: | Wissenschaften |
Medium: | Buch |
Reihe: | Methods in Molecular Biology |
Inhalt: |
xi
436 S. 51 s/w Illustr. 104 farbige Illustr. 436 p. 155 illus. 104 illus. in color. |
ISBN-13: | 9781493991815 |
ISBN-10: | 1493991817 |
Sprache: | Englisch |
Herstellernummer: | 978-1-4939-9181-5 |
Ausstattung / Beilage: | HC runder Rücken kaschiert |
Einband: | Gebunden |
Redaktion: |
Winn, Louise M.
Hansen, Jason M. |
Herausgeber: | Jason M Hansen/Louise M Winn |
Auflage: | 2nd ed. 2019 |
Hersteller: |
Springer US
Springer New York Methods in Molecular Biology |
Maße: | 260 x 183 x 30 mm |
Von/Mit: | Louise M. Winn (u. a.) |
Erscheinungsdatum: | 09.05.2019 |
Gewicht: | 1,034 kg |