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Diagnostic Molecular Biology
Taschenbuch von Chang-Hui Shen
Sprache: Englisch

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Beschreibung
Diagnostic Molecular Biology, Second Edition describes the fundamentals of molecular biology in a clear, concise manner with each technique explained within its conceptual framework and current applications of clinical laboratory techniques comprehensively covered. This targeted approach covers the principles of molecular biology, including basic knowledge of nucleic acids, proteins and chromosomes; the basic techniques and instrumentations commonly used in the field of molecular biology, including detailed procedures and explanations; and the applications of the principles and techniques currently employed in the clinical laboratory. Topics such as whole exome sequencing, whole genome sequencing, RNA-seq, and ChIP-seq round out the discussion. Fully updated, this new edition adds recent advances in the detection of respiratory virus infections in humans, like influenza, RSV, hAdV, hRV but also corona. This book expands the discussion on NGS application and its role in future precision medicine.
Diagnostic Molecular Biology, Second Edition describes the fundamentals of molecular biology in a clear, concise manner with each technique explained within its conceptual framework and current applications of clinical laboratory techniques comprehensively covered. This targeted approach covers the principles of molecular biology, including basic knowledge of nucleic acids, proteins and chromosomes; the basic techniques and instrumentations commonly used in the field of molecular biology, including detailed procedures and explanations; and the applications of the principles and techniques currently employed in the clinical laboratory. Topics such as whole exome sequencing, whole genome sequencing, RNA-seq, and ChIP-seq round out the discussion. Fully updated, this new edition adds recent advances in the detection of respiratory virus infections in humans, like influenza, RSV, hAdV, hRV but also corona. This book expands the discussion on NGS application and its role in future precision medicine.
Über den Autor
Chang-Hui Shen, PhD, is a Professor of Biology and Biochemistry at the College of Staten Island and the Graduate Center, City University of New York. He earned his B.S. and M.S. at the National Chung-Hsing University, Taiwan, and his Ph.D. at the University of Edinburgh, UK. He was a visiting fellow of the National Institutes of Health before joining the City University of New York.

Dr. Shen's research focuses on the mechanism of gene expression, with an emphasis on epigenetic regulation in gene activation. His lab utilizes the breadth of current and advanced techniques in molecular biology and biochemistry. He has published dozens of articles throughout his career, and his research has been supported by several agencies, including NATO, NIH, and NSF.
Inhaltsverzeichnis

1. Nucleic Acids: DNA and RNA 2. Nucleic Acid-Based Cellular Activities - DNA Replication, Damage, and Repair 3. Gene Expression: Transcription of the Genetic Code 4. Gene Expression: Translation of the Genetic Code 5. The Genome 6. Extraction and Purification of Nucleic Acids 7. Quantification and Analysis of Nucleic Acids 8. Extraction and Purification of Proteins 9. Quantification and Analysis of Proteins 10. Amplification of Nucleic Acids 11. Characterization of Nucleic Acids and Proteins 12. Techniques in Sequencing 13. Genome and Transriptome Analysis 14. Molecular Diagnosis of Chromosomal Disorders 15. Molecular Diagnosis of Gene Mutation and Inherited Diseases 16. Molecular Diagnosis of Infectious Diseases 17. The Biology of SARS-CoV-2 and the Molecular Diagnosis of COVID-19 18. Guidance for Molecular Diagnostic Laboratory

Details
Erscheinungsjahr: 2023
Fachbereich: Grundlagen
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Inhalt: Kartoniert / Broschiert
ISBN-13: 9780323917889
ISBN-10: 0323917887
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Shen, Chang-Hui
Hersteller: Elsevier Science & Technology
Maße: 212 x 277 x 32 mm
Von/Mit: Chang-Hui Shen
Erscheinungsdatum: 29.06.2023
Gewicht: 1,574 kg
Artikel-ID: 125755687
Über den Autor
Chang-Hui Shen, PhD, is a Professor of Biology and Biochemistry at the College of Staten Island and the Graduate Center, City University of New York. He earned his B.S. and M.S. at the National Chung-Hsing University, Taiwan, and his Ph.D. at the University of Edinburgh, UK. He was a visiting fellow of the National Institutes of Health before joining the City University of New York.

Dr. Shen's research focuses on the mechanism of gene expression, with an emphasis on epigenetic regulation in gene activation. His lab utilizes the breadth of current and advanced techniques in molecular biology and biochemistry. He has published dozens of articles throughout his career, and his research has been supported by several agencies, including NATO, NIH, and NSF.
Inhaltsverzeichnis

1. Nucleic Acids: DNA and RNA 2. Nucleic Acid-Based Cellular Activities - DNA Replication, Damage, and Repair 3. Gene Expression: Transcription of the Genetic Code 4. Gene Expression: Translation of the Genetic Code 5. The Genome 6. Extraction and Purification of Nucleic Acids 7. Quantification and Analysis of Nucleic Acids 8. Extraction and Purification of Proteins 9. Quantification and Analysis of Proteins 10. Amplification of Nucleic Acids 11. Characterization of Nucleic Acids and Proteins 12. Techniques in Sequencing 13. Genome and Transriptome Analysis 14. Molecular Diagnosis of Chromosomal Disorders 15. Molecular Diagnosis of Gene Mutation and Inherited Diseases 16. Molecular Diagnosis of Infectious Diseases 17. The Biology of SARS-CoV-2 and the Molecular Diagnosis of COVID-19 18. Guidance for Molecular Diagnostic Laboratory

Details
Erscheinungsjahr: 2023
Fachbereich: Grundlagen
Genre: Biologie
Rubrik: Naturwissenschaften & Technik
Medium: Taschenbuch
Inhalt: Kartoniert / Broschiert
ISBN-13: 9780323917889
ISBN-10: 0323917887
Sprache: Englisch
Einband: Kartoniert / Broschiert
Autor: Shen, Chang-Hui
Hersteller: Elsevier Science & Technology
Maße: 212 x 277 x 32 mm
Von/Mit: Chang-Hui Shen
Erscheinungsdatum: 29.06.2023
Gewicht: 1,574 kg
Artikel-ID: 125755687
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