Gaetano Valenza, Ph.D., is a Senior Researcher at the University of Pisa and head of the Neuro-Cardiovascular Intelligence lab at the University of Pisa, Italy. His research interests include statistical and nonlinear biomedical signal and image processing, cardiovascular and neural modeling, physiologically-interpretable artificial intelligence systems, and wearable systems for physiological monitoring. Applications of his research include the assessment of autonomic nervous system activity on cardiovascular control, brain-heart interactions, affective computing, assessment of mood and mental/neurological disorders. He is an author of more than 250 international scientific contributions in these fields published in peer-reviewed international journals, conference proceedings, books and book chapters. He has been involved in several international research projects and has been serving as guest/associate editor for several scientific journals.

Vincenzo Catrambone, Ph.D., is a post-doc fellow at the University of Pisa and member of the Neuro-Cardiovascular Intelligence lab at the University of Pisa, Italy. His research work spans statistical and nonlinear biomedical signal and image processing, cardiovascular and neural modeling, physiologically-interpretable artificial intelligence systems. Applications of his research include the assessment of brain-heart interactions in physiological and pathological conditions, brain-computer interfaces, affective computing, assessment of mood and mental/neurological disorders, and neurorehabilitation. His Ph.D. Thesis was specifically focused on the estimation of functional brain-heart interplay. He is an author of several international scientific contributions in these fields published in peer-reviewed international journals, and conference proceedings. He is involved in several international research projects, and in the past, he has been visiting researcher at the École Normale Supérieure de Lyon,France, and at the Maastricht University, Netherlands.

Provides an overview of the Brain-Heart Interplay quantifiers, and the advanced methods for the assessment of health and disease states

Describes contemporary brain monitoring techniques with heartbeat dynamics

Includes real-life applications of brain and heartbeat data

1. Physiology of Brain-Heart Interplay.- 2. Brain and Heart Signal Processing Methodology.- 3. Quantification of Functional Brain-Heart Interplay.- 4. Exemplary Applications to Real Brain and Heartbeat Data.- 5. Future Direction of Research and Prospective Applications using Functional Brain-Heart Interplay Assessment