Includes cutting-edge methods and protocols

Provides step-by-step detail essential for reproducible results

Contains key notes and implementation advice from the experts

Overview: of Mass Spectrometry Based Metabolomics: Opportunities and Challenges.- Global Metabolic Profiling using Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry.- LC-MS Profiling to Link Metabolic and Phenotypic Diversity in Plant Mapping Populations.- Mitochondrial Metabolomics Using High-Resolution Fourier-Transform Mass Spectrometry.- Sample Preparation Methods for LC-MS Based Global Aqueous Metabolite Profiling.- Methods of Discovery-Based and Targeted Metabolite Analysis by Comprehensive Two-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry Detection.- Analysis of Mouse Liver Metabolites by GC×GC-TOF MS.- Metabolite Fingerprinting by Capillary Electrophoresis-Mass Spectrometry.- Quantitative Metabolomic Profiling using Dansylation Isotope Labeling and Liquid Chromatography Mass Spectrometry.- Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS Analysis.- Stable Isotope Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS.- Multiplexed, Quantitative and Targeted Metabolite Profiling by LC-MS/MRM.- Multi-Dimensional Mass Spectrometry-Based Shotgun Lipidomics.- Comprehensive Quantitative Determination of PUFA-Related Bioactive Lipids for Functional Lipidomics using High Resolution Mass Spectrometry.- Ultra-Performance Liquid Chromatography Mass Spectrometry Targeted Profiling of Bile Acids: Application to Serum, Liver Tissue and Cultured Cells of Different Species.- Analysis of Volatile Organic Compounds in Exhaled Breath by Gas Chromatography-Mass Spectrometry combined with Chemometric Analysis.- Headspace SPME-GC-MS Metabolomics Analysis of Urinary Volatile Organic Compounds (VOCs).- Metabolite Profiling by Direct Analysis in Real Time Mass Spectrometry.- Analysis of Dried Blood Spots using DESI Mass Spectrometry.- DESI-MS Imaging of Lipids and Metabolites from Biological Samples.- Metabolic Imaging using Nanostructure-Initiator Mass Spectrometry(NIMS).- Statistical Analysis and Modeling of Mass Spectrometry-Based Metabolomics Data.