Ru-Rong Ji: Neuroimmune Interactions in Pain

Cover: 9783031292309 | Neuroimmune Interactions in Pain | Mechanisms and Therapeutics | Buch

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Sprache: Englisch

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Beschreibung

As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be severely limited. Anti-inflammatory drugs can only do so much, while painkillers like opioids have led to crippling addictions and fatal overdoses. The subject of the book is the role of immune cells, including glial cells, and neuroimmune interactions in chronic pain. The book begins by examining the preclinical and clinical evidence supporting the involvement of non-neuronal cells in chronic pain. It discusses the interactions between non-neuronal cells and neurons in the regulation of chronic pain. It then presents the implications of these findings, including promising and emerging treatments such as specialized pro-resolving mediators (SPMs, such as resolvins and protectins), immune cell therapy, and complementary and alternative medicine, as well as neuromodulation and regenerative medicine, which may prove to be theturning point for hundreds of millions of patients world-wide who struggle to escape from the shadow of chronic pain. The book presents ground-breaking research that will alter current perspectives on chronic pain.

Über den Autor

Dr. Ru-Rong Ji, is a Professor of Anesthesiology, and the Director of the Center for Translational Pain Medicine at the Duke University Medical Center in Durham, North Carolina, USA.

Dr. Jianguo Cheng is Professor of Anesthesiology and the Director of Cleveland Clinic Multidisciplinary Pain Medicine Fellowship Program. He works in the departments of Pain Management and Neurosciences at the Cleveland Clinic in Cleveland, Ohio, USA. He is Past President of the American Academy of Pain Medicine.

Jasmine Ji is a Neuroscience student at Wellesley College in Wellesley, Massachusetts, USA.

Zusammenfassung

Examines the involvement of non-neuronal cells in chronic pain

Presents potential new treatments for chronic pain such as specialized immune cell therapy

Offers an introduction to acute and chronic pain in the context of the opioid crisis and the COVID pandemic

Inhaltsverzeichnis

Introduction to Acute, Chronic, and Episodic Pain.- Inflammation and Pain.- Animal Models of Pain and Anti-inflammatory Treatments.- Inflammatory Mediators, Nociceptors, and Their Interactions in Pain.- Immune and Glial Cells in Pain and Their Interactions with Nociceptive Neurons.- Sex Differences in Neuroimmune Interactions and Pain.- Neuroimmune Interactions in Itch.- Toll-like Receptors in Pain and Itch.- Immunotherapy and Pain.- Cell Therapy and Regenerative Pain Medicine - Preclinical Studies.- Cell-based Therapies in Pain Management.- Platelet-Rich Plasma and Autologous Conditioned Serum: Non-Cellular Biologic Therapies for Neuroimmune Modulation and the Treatment of Arthritis Pain.- Exercise and Diet in the Control of Inflammation and Pain.- Mechanism-Based Pain Therapies.- Neuromodulation in Pain Management.- What Patients Need to Know about Pain Therapy?.

Details

Erscheinungsjahr:	2023
Fachbereich:	Therapie
Genre:	Medizin
Rubrik:	Wissenschaften
Medium:	Buch
Inhalt:	x 364 S. 4 s/w Illustr. 41 farbige Illustr. 364 p. 45 illus. 41 illus. in color.
ISBN-13:	9783031292309
ISBN-10:	3031292308
Sprache:	Englisch
Ausstattung / Beilage:	HC runder Rücken kaschiert
Einband:	Gebunden
Redaktion:	Ji, Ru-Rong Ji, Jasmine Cheng, Jianguo
Herausgeber:	Ru-Rong Ji/Jianguo Cheng/Jasmine Ji
Hersteller:	Springer International Publishing
Maße:	241 x 160 x 26 mm
Von/Mit:	Ru-Rong Ji (u. a.)
Erscheinungsdatum:	06.05.2023
Gewicht:	0,729 kg

Artikel-ID: 126637274