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Simvastatin Solid Dispersion Prepared By Microwave Fusion Technique
Taschenbuch von Haresh Chaudhary (u. a.)
Sprache: Englisch

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Beschreibung
Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-free solid dispersions and to enhance the solubility and dissolution rate of simvastatin by a solid dispersion.
Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-Simvastatin, a crystalline substance, is a widely used drug for the treatment of hypercholesterolemia. It is a BCS class II drug, having low aqueous solubility (0.76 mg/L) exhibiting poor dissolution pattern and low oral bioavailability (5%). The purpose of this study was to apply the attractive technique of the microwaves fusion for the preparation of solvent-free solid dispersions and to enhance the solubility and dissolution rate of simvastatin by a solid dispersion.
Über den Autor
Haresh Chaudhary has completed [...] and [...] from Shri Sarvajanik Pharmacy College,Mehsana and currently working in Formulation Development Department at Cadila Healthcare Ltd, Ahmedabad. He is energetic person with positive attitude toward his goal.
Details
Erscheinungsjahr: 2014
Fachbereich: Toxikologie
Genre: Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Wissenschaften
Medium: Taschenbuch
Inhalt: 124 S.
ISBN-13: 9783846504055
ISBN-10: 384650405X
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Chaudhary, Haresh
Patel, B. N.
Patel, D. M.
Hersteller: LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU: OmniScriptum GmbH & Co. KG, Bahnhofstr. 28, D-66111 Saarbrücken, info@akademikerverlag.de
Maße: 220 x 150 x 8 mm
Von/Mit: Haresh Chaudhary (u. a.)
Erscheinungsdatum: 13.02.2014
Gewicht: 0,203 kg
Artikel-ID: 105444767
Über den Autor
Haresh Chaudhary has completed [...] and [...] from Shri Sarvajanik Pharmacy College,Mehsana and currently working in Formulation Development Department at Cadila Healthcare Ltd, Ahmedabad. He is energetic person with positive attitude toward his goal.
Details
Erscheinungsjahr: 2014
Fachbereich: Toxikologie
Genre: Mathematik, Medizin, Naturwissenschaften, Technik
Rubrik: Wissenschaften
Medium: Taschenbuch
Inhalt: 124 S.
ISBN-13: 9783846504055
ISBN-10: 384650405X
Sprache: Englisch
Ausstattung / Beilage: Paperback
Einband: Kartoniert / Broschiert
Autor: Chaudhary, Haresh
Patel, B. N.
Patel, D. M.
Hersteller: LAP LAMBERT Academic Publishing
Verantwortliche Person für die EU: OmniScriptum GmbH & Co. KG, Bahnhofstr. 28, D-66111 Saarbrücken, info@akademikerverlag.de
Maße: 220 x 150 x 8 mm
Von/Mit: Haresh Chaudhary (u. a.)
Erscheinungsdatum: 13.02.2014
Gewicht: 0,203 kg
Artikel-ID: 105444767
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