Professor of Medicine

Department of Medicine

Johns Hopkins School of Medicine

Baltimore, MD

Mark A. Perazella, MD, FACP

Professor of Medicine

Section of Nephrology

Department of Internal Medicine

New Haven, CT

Explains how the pathogenesis of tubulointerstitial nephritis has changed since its discovery

Includes up-to-date educational materials that benefit both basic and clinical scientists

Written by experts in the field

History and Epidemiology.- A history of its conceptual evolution.- Epidemiology of tubulointerstitial nephritis.- Pathogenesis.- Pathogenesis of Acute Tubulointerstitial Nephritis.- Causes of Acute Tubulointerstitial Nephritis.- Drugs associated with Acute Tubulointerstitial Nephritis.- Viral-induced Tubulointerstitial Nephritis.- Bacterial and parasitic-related tubulointerstitial nephritis.- Tubulointerstitial nephritis due to autoimmune diseases.- IgG4-Related Tubulointerstitial Disease.- Anti-brush border antibody (ABBA)-associated tubulointerstitial disease.- Transplant Rejection and Infection Associated Tubulointerstitial Nephritis.- Non-immune Mediated.-Genetic Diseases Associated with Tubulointerstitial Nephritis.- Cystinosis.- Chronic tubulointerstitial nephritis: Hypokalemia, hyperoxaluria, and hyperuricemia.- Non-immunological Causes of Tubulointerstitial Disease.- Reflux and Obstructive Nephropathy.- Aristolochic Acid Nephropathy and Balkan Nephropathy.- Chronic Kidney Disease of Unknown Etiology.- Infiltrative Disease of the Tubulointerstitium.- Diagnosis.- Clinical features and laboratory findings in acute tubulointerstitial nephritis.- Imaging modalities for acute tubulointerstitial nephritis.- Pathology of Tubulointerstitial Nephritis.- Treatment.- Management of Tubulointerstitial Nephritis.- Prognosis/Outcomes.- Prognosis and outcomes of acute tubulointerstitial nephritis.