PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY

Unit 1: The Cell 1. Cellular Biology 2. Genes and Genetic Diseases 3. Epigenetics and Disease 4. Altered Cellular and Tissue Biology 5. Fluids and Electrolytes, Acids and Bases

Unit 2: Mechanisms of Self-Defense 6. Innate Immunity: Inflammation and Wound Healing 7. Adaptive Immunity 8. Alterations in Immunity NEW 9. Infection and Defects in Mechanisms of Defense 10. Stress and Disease

Unit 3: Cellular Proliferation: Cancer 11. Biology of Cancer 12. Cancer Epidemiology 13. Cancer in Children and Adolescents

PART TWO: BODY SYSTEMS AND DISEASES

Unit 4: The Neurologic System 14. Structure and Function of the Neurologic System 15. Pain, Temperature, Sleep, and Sensory Function 16. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function 17. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction 18. Alterations of Neurologic Function in Children

Unit 5: The Endocrine System 19. Mechanisms of Hormonal Regulation 20. Alterations of Hormonal Regulation 21. Obesity and Disorders of Nutrition NEW

Unit 6: The Hematologic System 22. Structure and Function of the Hematologic System 23. Alterations of Hematologic Function 24. Alterations of Hematologic Function in Children

Unit 7: The Cardiovascular and Lymphatic Systems 25. Structure and Function of the Cardiovascular and Lymphatic Systems 26. Alterations of Cardiovascular Function 27. Alterations of Cardiovascular Function in Children

Unit 8: The Pulmonary System 28. Structure and Function of the Pulmonary System 29. Alterations of Pulmonary Function 30. Alterations of Pulmonary Function in Children

Unit 9: The Renal and Urologic Systems 31. Structure and Function of the Renal and Urologic Systems 32. Alterations of Renal and Urinary Tract Function 33. Alterations of Renal and Urinary Tract Function in Children

Unit 10: The Reproductive Systems 34. Structure and Function of the Reproductive Systems 35. Alterations of the Female Reproductive System 36. Alterations of the Male Reproductive System

Unit 11: The Digestive System 37. Structure and Function of the Digestive System 38. Alterations of Digestive Function 39. Alterations of Digestive Function in Children

Unit 12: The Musculoskeletal and Integumentary Systems 40. Structure and Function of the Musculoskeletal System 41. Alterations of Musculoskeletal Function 42. Alterations of Musculoskeletal Function in Children 43. Structure, Function, and Disorders of the Integument 44. Alterations of the Integument in Children

Glossary Index