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Beschreibung
According to the World Health Organization, approximately one third of the world¿s population is latently infected with Mycobacterium tuberculosis (M. tb [LTBI]), of whom about 9 million have active tuberculosis (TB). It is estimated that approximately 2 million individuals die each year from active TB. An estimated 14.4% of these individuals have HIV and M. tb co-infection.
TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition.
This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host¿s immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarette smokingand aging, and strategies to restore favorable immune responses against this deadly pathogen.
TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition.
This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host¿s immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarette smokingand aging, and strategies to restore favorable immune responses against this deadly pathogen.
According to the World Health Organization, approximately one third of the world¿s population is latently infected with Mycobacterium tuberculosis (M. tb [LTBI]), of whom about 9 million have active tuberculosis (TB). It is estimated that approximately 2 million individuals die each year from active TB. An estimated 14.4% of these individuals have HIV and M. tb co-infection.
TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition.
This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host¿s immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarette smokingand aging, and strategies to restore favorable immune responses against this deadly pathogen.
TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition.
This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host¿s immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarette smokingand aging, and strategies to restore favorable immune responses against this deadly pathogen.
Über den Autor
Vishwanath Venketaraman
Department of Basic Medical Sciences
Western University of Health Sciences
Pomona, CA
Zusammenfassung
Editor and contributors are internationally recognized experts in TB research
Discusses the latest findings on comorbidity between TB and various conditions
Novel focus on the effects of chronic smoking and ageing on immune response against TB
Inhaltsverzeichnis
1. Co-Morbidities in HIV and Tuberculosis. Elizabeth Luke Hanna, Dept of Clinical Research, National institute for Research in TB, India.- 2. Diabetes and Tuberculosis. Blanca Restrepo, Dept. of Microbiology, Immunology, Molecular Genetics, UT Health - San Antonio.- 3. Extrapulmonary Tuberculosis. Johan Feuth Schoeman, Dept of Neurology, University of Stellenbosch.- 4. Animal Models to Study Adaptive Immune Responses Against M. tb Infection. Janice J. Endsley, Dept of Pathology, UT Medical Branch.- 5. Immunodiagnosis of Tuberculosis. Keertan Dheda, Dept of Respiratory Medicine, University of Cape Town.- 6. Granulomatous Responses Against M. tb Infection. Selvakumar Subbian, Dept of Biomedical and Health Sciences, Rutgers University.- 7. Host-Directed Therapies for Tuberculosis. Vishwanath Venketaraman (editor).
Details
Erscheinungsjahr: | 2018 |
---|---|
Fachbereich: | Therapie |
Genre: | Medizin |
Rubrik: | Wissenschaften |
Medium: | Buch |
Inhalt: |
x
144 S. 2 s/w Illustr. 12 farbige Illustr. 144 p. 14 illus. 12 illus. in color. |
ISBN-13: | 9783319973661 |
ISBN-10: | 3319973665 |
Sprache: | Englisch |
Herstellernummer: | 978-3-319-97366-1 |
Ausstattung / Beilage: | HC runder Rücken kaschiert |
Einband: | Gebunden |
Redaktion: | Venketaraman, Vishwanath |
Herausgeber: | Vishwanath Venketaraman |
Auflage: | 1st ed. 2018 |
Hersteller: |
Springer International Publishing
Springer International Publishing AG |
Maße: | 241 x 160 x 15 mm |
Von/Mit: | Vishwanath Venketaraman |
Erscheinungsdatum: | 10.10.2018 |
Gewicht: | 0,407 kg |
Über den Autor
Vishwanath Venketaraman
Department of Basic Medical Sciences
Western University of Health Sciences
Pomona, CA
Zusammenfassung
Editor and contributors are internationally recognized experts in TB research
Discusses the latest findings on comorbidity between TB and various conditions
Novel focus on the effects of chronic smoking and ageing on immune response against TB
Inhaltsverzeichnis
1. Co-Morbidities in HIV and Tuberculosis. Elizabeth Luke Hanna, Dept of Clinical Research, National institute for Research in TB, India.- 2. Diabetes and Tuberculosis. Blanca Restrepo, Dept. of Microbiology, Immunology, Molecular Genetics, UT Health - San Antonio.- 3. Extrapulmonary Tuberculosis. Johan Feuth Schoeman, Dept of Neurology, University of Stellenbosch.- 4. Animal Models to Study Adaptive Immune Responses Against M. tb Infection. Janice J. Endsley, Dept of Pathology, UT Medical Branch.- 5. Immunodiagnosis of Tuberculosis. Keertan Dheda, Dept of Respiratory Medicine, University of Cape Town.- 6. Granulomatous Responses Against M. tb Infection. Selvakumar Subbian, Dept of Biomedical and Health Sciences, Rutgers University.- 7. Host-Directed Therapies for Tuberculosis. Vishwanath Venketaraman (editor).
Details
Erscheinungsjahr: | 2018 |
---|---|
Fachbereich: | Therapie |
Genre: | Medizin |
Rubrik: | Wissenschaften |
Medium: | Buch |
Inhalt: |
x
144 S. 2 s/w Illustr. 12 farbige Illustr. 144 p. 14 illus. 12 illus. in color. |
ISBN-13: | 9783319973661 |
ISBN-10: | 3319973665 |
Sprache: | Englisch |
Herstellernummer: | 978-3-319-97366-1 |
Ausstattung / Beilage: | HC runder Rücken kaschiert |
Einband: | Gebunden |
Redaktion: | Venketaraman, Vishwanath |
Herausgeber: | Vishwanath Venketaraman |
Auflage: | 1st ed. 2018 |
Hersteller: |
Springer International Publishing
Springer International Publishing AG |
Maße: | 241 x 160 x 15 mm |
Von/Mit: | Vishwanath Venketaraman |
Erscheinungsdatum: | 10.10.2018 |
Gewicht: | 0,407 kg |
Warnhinweis