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Scientific research into the origins of life remains exploratory and speculative. Science has no definitive answer to the biggest questions--"What is life?" and "How did life begin on earth?" In this book, Jan Spitzer reconceptualizes origins research by exploiting a modern understanding of non-covalent molecular forces and covalent bond formation--a physicochemical approach propounded originally by Linus Pauling and Max Delbrück. Spitzer develops the Pauling-Delbrück premise as a physicochemical jigsaw puzzle that identifies key stages in life's emergence, from the formation of first oceans, tidal sediments, and proto-biofilms to progenotes, proto-cells and the first cellular organisms.
Scientific research into the origins of life remains exploratory and speculative. Science has no definitive answer to the biggest questions--"What is life?" and "How did life begin on earth?" In this book, Jan Spitzer reconceptualizes origins research by exploiting a modern understanding of non-covalent molecular forces and covalent bond formation--a physicochemical approach propounded originally by Linus Pauling and Max Delbrück. Spitzer develops the Pauling-Delbrück premise as a physicochemical jigsaw puzzle that identifies key stages in life's emergence, from the formation of first oceans, tidal sediments, and proto-biofilms to progenotes, proto-cells and the first cellular organisms.
A Note about This “Story” xvii
Preface xix
Acknowledgments xxv
Introduction: A Physicochemical Framework for Origins Research 1
1 Understanding Biological Matter 19
2 Defining the Origins Problem 31
3 Structured Bacterial Life: No Bag of Enzymes 53
4 Bacterial Non-covalent Forces and Phase Separation 65
5 Bacterial Crowding and Vectorial Organization 85
6 The Jigsaw Puzzle Pieces 103
7 The Physicochemical Roots of Darwinian Evolution 129
8 An Unexplored Experimental Paradigm of Cyclic Processes 141
Summary 157
Appendix: Screened Electrostatic Interactions in Crowded Colloidal Systems 165
Notes 171
References 191
Index 217
| Erscheinungsjahr: | 2021 |
|---|---|
| Genre: | Biologie |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Buch |
| Inhalt: | Einband - fest (Hardcover) |
| ISBN-13: | 9780262045575 |
| ISBN-10: | 0262045575 |
| Sprache: | Englisch |
| Einband: | Gebunden |
| Autor: | Spitzer, Jan |
| Hersteller: | MIT Press Ltd |
| Maße: | 159 x 236 x 24 mm |
| Von/Mit: | Jan Spitzer |
| Erscheinungsdatum: | 09.02.2021 |
| Gewicht: | 0,53 kg |
A Note about This “Story” xvii
Preface xix
Acknowledgments xxv
Introduction: A Physicochemical Framework for Origins Research 1
1 Understanding Biological Matter 19
2 Defining the Origins Problem 31
3 Structured Bacterial Life: No Bag of Enzymes 53
4 Bacterial Non-covalent Forces and Phase Separation 65
5 Bacterial Crowding and Vectorial Organization 85
6 The Jigsaw Puzzle Pieces 103
7 The Physicochemical Roots of Darwinian Evolution 129
8 An Unexplored Experimental Paradigm of Cyclic Processes 141
Summary 157
Appendix: Screened Electrostatic Interactions in Crowded Colloidal Systems 165
Notes 171
References 191
Index 217
| Erscheinungsjahr: | 2021 |
|---|---|
| Genre: | Biologie |
| Rubrik: | Naturwissenschaften & Technik |
| Medium: | Buch |
| Inhalt: | Einband - fest (Hardcover) |
| ISBN-13: | 9780262045575 |
| ISBN-10: | 0262045575 |
| Sprache: | Englisch |
| Einband: | Gebunden |
| Autor: | Spitzer, Jan |
| Hersteller: | MIT Press Ltd |
| Maße: | 159 x 236 x 24 mm |
| Von/Mit: | Jan Spitzer |
| Erscheinungsdatum: | 09.02.2021 |
| Gewicht: | 0,53 kg |
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