Textbook of Receptor Pharmacology

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Beschreibung

For the past four decades, University College London has offered a renowned course on receptor pharmacology. Originating from this course, the perennially bestselling Textbook of Receptor Pharmacology has presented in-depth coverage of this rapidly expanding area of research. This third edition continues to combine current understanding of classical quantitative pharmacology and drug-receptor interactions with the basics of receptor structure and signal transduction mechanisms, providing an integrated analysis of the mechanisms of drug action at membrane receptors.

The hallmark of this popular text is the uniting of four major approaches to the study of receptors:

Molecular investigation of receptor structure

Quantitative functional studies of agonists and antagonists

Ligand binding

Signal transduction at the cell membrane

Maintaining the second edition's focus on cell membrane receptors and the immediate signal transduction events at the membrane, this edition includes updated chapters on receptor structure and signal transduction by G-proteins and tyrosine kinases as well as enhancements to the quantitative treatment of drug-receptor interactions. Several chapters contain problems and worked-out solutions, giving students the ability to test their comprehension of the material. Hundreds of diagrams and figures further enhance the text.

A time-saving resource and comprehensive learning tool, Textbook of Receptor Pharmacology, Third Edition carries on the tradition of providing in-depth, up-to-date coverage of this critical area that is both fundamental to the science of pharmacology and on the cutting edge of new drug development.

The hallmark of this popular text is the uniting of four major approaches to the study of receptors:

Molecular investigation of receptor structure

Quantitative functional studies of agonists and antagonists

Ligand binding

Signal transduction at the cell membrane

Inhaltsverzeichnis

Drug-Receptor Interactions: Classical Approaches to the Study of Drug-Receptor Interactions. Molecular Structure of Receptors: Structure and Function 7-TM G-Protein Coupled Receptors. The Structure of Ligand-Gated Ion Channels. Molecular Structure of Receptor Tyrosine Kinases. Ligand-Binding Studies of Receptors: Direct Measurement of Drug Binding to Receptors. Transduction of the Receptor Signal: Receptors Linked to Ion Channels: Mechanisms of Activation and Block. G-Proteins. Signal Transduction through Protein Tyrosine Kinases. Receptors as Pharmaceutical Targets: Receptors as Pharmaceutical Targets.

Details

Medium:	Taschenbuch
ISBN-13:	9781032099378
ISBN-10:	1032099372
Sprache:	Englisch
Redaktion:	Foreman, John C. Johansen, Torben Gibb, Alasdair J.
Auflage:	3. Aufl.
Hersteller:	CRC Press Taylor & Francis
Verantwortliche Person für die EU:	preigu, Ansas Meyer, Lengericher Landstr. 19, D-49078 Osnabrück, mail@preigu.de
Abbildungen:	128 SW-Abb., 8 Farbabb.
Maße:	18 x 178 x 254 mm
Von/Mit:	John C. Foreman (u. a.)
Gewicht:	0,84 kg

Artikel-ID: 131007830

Inhaltsverzeichnis

Details

Medium:	Taschenbuch
ISBN-13:	9781032099378
ISBN-10:	1032099372
Sprache:	Englisch
Redaktion:	Foreman, John C. Johansen, Torben Gibb, Alasdair J.
Auflage:	3. Aufl.
Hersteller:	CRC Press Taylor & Francis
Verantwortliche Person für die EU:	preigu, Ansas Meyer, Lengericher Landstr. 19, D-49078 Osnabrück, mail@preigu.de
Abbildungen:	128 SW-Abb., 8 Farbabb.
Maße:	18 x 178 x 254 mm
Von/Mit:	John C. Foreman (u. a.)
Gewicht:	0,84 kg